The drug "Clion D 100" (doctors' reviews confirm this) is an effective antiprotozoal and antifungal agent. The drug is used topically in gynecology. A remedy is given in the form of vaginal tablets (candles). Active ingredients: miconazole nitrate, metronidazole.
The drug "Klion D" (candles), reviews of gynecologists indicate this, shows the activity of a relatively large number of pathogenic bacteria, including dermatophytes, some gram-positive microbes, yeast fungi. The drug helps to eliminate itching, which often accompanies infectious lesions. Means "Klion D" (doctors' reviews confirm this) does not change the pH and does not break the composition of the vaginal microflora.
Metronidazole for intravaginal use is absorbed into the systemic circulation. The maximum content of the component is found after six to twelve hours. This concentration is half that level, which is achieved in one to three hours after a single application of the equivalent dosage of metronidazole orally.
Mitconazole nitrate is slightly absorbed when administered intravaginally. Eight hours after application of the order of 90% of the component is found in the vagina.
The drug "Klion D" (doctors' reviews confirm this) is used to treat nonspecific, candida and trichomonas vaginitis.
In the latter case, the suppository is administered per day. Treatment is carried out for ten days. Local use of the medication is combined with oral administration of metronidazole.
Treatment of nonspecific or candidal vaginitis is carried out for ten days. In this case, it is recommended to administer the suppository twice a day. The doctor (if necessary) can recommend an additional intake of metronidazole inside.
Before the introduction of the vaginal tablet "Clion D" (the experts' reviews confirm this), you should moisten it with chilled boiled water.
When using the drug, the occurrence of irritation reactions is likely: itching, burning, soreness, a feeling of discomfort. In some cases mucous discharges with mild odor (or odorless) may be noted. A sexual partner may feel a burning sensation or irritation of the penis.
In some cases, against the background of treatment with the drug "Klion D" (reviews of patients confirm this), there was diarrhea, dryness or metallic taste in the oral cavity, a change in taste, a decrease in appetite, nausea, constipation. Sometimes there were vomiting, spastic pains in the peritoneum.
The drug "Klion D" can provoke leukocytosis, leukopenia, dizziness or headache. Some patients were allergic to the drug, there was a rash.
Among the side effects are also frequent urination, a change in the color of urine.
The drug "Clion D" is contraindicated in cases of leukopenia (history, including), blood disease, coordination disorder, organic lesions of the central nervous system (epilepsy including). Do not prescribe medicine for liver failure, hypersensitivity. Contraindications include pregnancy and lactation.
Throughout the therapeutic course, experts recommend refraining from sexual contacts.
To prevent re-infection, the doctor can recommend the treatment of the sexual partner with the oral "Metronidazole" (regardless of whether or not the partner has symptoms of pathology).
It should be borne in mind that the simultaneous use of the drug "Clion D" with lithium preparations provokes an increase in the concentration of the latter in the plasma.