The drug "Misoprostol". Instructions for use

Tablets "Misoprostol" - a drug that has a gastroprotective effect. The drug helps increase production of bicarbonate and protective mucus, strengthening in the mucosa of the bloodstream. The drug "Misoprostol" (the instruction contains such data) speeds up the healing process of stomach or duodenal ulcers, erosions, and also in some cases prevents their formation. The agent has an effect on the parental cells in the stomach. The activity of the drug is noted after thirty minutes after administration. The duration of the action is from 3 to 6 hours. The medication helps to reduce the myometrium in the smooth muscles, widens the uterine neck. Against the background of oral administration, rapid and complete absorption is observed. Eating food reduces absorption. The drug is metabolized in the liver and GIT walls.

The medicine "Misoprostol". Instructions. Appointment

A remedy for treatment and prevention of peptic ulcer of the duodenum and stomach, ulcerative gastrointestinal lesions on the basis of NSAID administration is recommended. In combination with the drug "Mifepristone", a medication is prescribed for the termination of pregnancy in the early periods (up to 42 days). The drug "Misoprostol" (instruction indicates this) is recommended for exacerbation of gastric ulcer, erosive gastroduodenitis.

Contraindications

Do not prescribe medicine as a gastroprotective agent in pregnancy. To the contraindications of the drug "Misoprostol" (experts' reviews confirm this) include age to eighteen years, the period of feeding, hypersensitivity. When prescribed for abortion, the drug is not recommended for anemia, hormone-dependent tumors, arterial hypertension, pathologies of the cardiovascular system. Do not prescribe medication for liver or kidney disease, bronchial asthma, when using intrauterine spirals (spiral before the start of therapy is removed). Contraindications include endocrine disorders (disorders of adrenal function, diabetes), glaucoma, suspicion of ectopic pregnancy. Caution when prescribing as a gastroprotective agent should be observed with inflammation in the intestines and other conditions predisposing to diarrhea. Correction of the dose is necessary with the probability of dehydration, epilepsy, hemopoiesis, IHD.

The drug "Misoprostol". Instructions for use

As a gastroprotective agent, medication is prescribed during a meal. For the prevention of NSAID-gastropathy, a drug in a dose of 400-800 μg / day is recommended. The amount of the funds is divided into 2-4 admissions. It is recommended to drink the drug simultaneously with NSAIDs and continue to use throughout the course of NSAID therapy. In the treatment of peptic ulcer and erosive gastroduodenitis , 800 μg / day is given in two or four doses. The duration of therapy is at least a month. For abortion, 400 μg of the drug is administered 36-48 hours after taking 600 mg of Mifepristone.