Use of this or that drug is associated with a certain risk. In addition, almost all medicines have a number of contraindications. Therefore, sensational pharmacological novelties should not be used without prior consultation, and even full-fledged care of doctors. It is to such drugs that "Avestin" belongs.
An injection in the eye ( necessary for the best absorption of the drug ) in this case is performed with the direct assistance of physicians. About how the procedure is carried out, in which cases it is carried out, what effect it has, you will learn from this article.
Generalized information about the medicine
"Avestin" is a medicinal product used in ophthalmology to suppress the growth of blood vessels. It is prescribed for patients suffering from a moist form of age-related macular degeneration, with diabetic retinopathy and other diseases.
By what principle does it operate? When is Avestin used? The description of the drug with the indication of the form of release, the components, frequency and features of use will help to answer all these most common questions.
What is the pharmacological group?
"Avestin" (a stab in the eye with its help helps to get rid of the growth of capillary nets and other ailments) refers primarily to antitumor drugs. It is also known as a multichannel antibody that selectively blocks the further proliferation of old and emerging new endothelium vessels. With it, you can stop the division of tumor cells and cancer cells, and restore your eyesight.
A few words about macular degeneration
Since medical terms, like the handwriting of doctors, are difficult for ordinary people to understand, we will try to make them easier and explain them in the most accessible language. So, most often this drug is prescribed to patients with a diagnosis of "makulodystrophy". What is it? And what influence does "Avestin" have on him? The injection with this drug is carried out under the aforementioned medical verdict. But does it give the expected result?
This ailment, as doctors say, arises with age, when the irreversible aging processes are already being launched in full. However, there are cases when the disease progressed in younger patients. Most often, it came against the backdrop of other health problems, for example, with the advanced stage of myopia. What is the cause of this ailment? And what consequences can it lead to?
So, that's what the doctors say about the illness. Over time, there is degeneration of the walls of the vessels, because of what their number and number increases. They themselves are displaced under the retina, begin to crush, and later completely destroy the "yellow spot".
Recall that it is necessary for us for a full-fledged view. This spot makes it possible to examine objects in detail, including the smallest elements and additions. It is believed that if you do not use Avestin on time (a stab in the eye in this case will help to get rid of possible health problems), the further growth of blood vessels can lead to complete blindness. At the moment about 12-15 people out of 1000 suffer from such a disease.
What methods are treated?
Like any other disease, macular degeneration has its own peculiarities and stages of development. For example, it is conditionally divided into a "wet" and "dry" variety. In particular, in the treatment of "wet" macular degeneration, laser therapy is most often used. However, this approach, as practice shows, does not always allow to maintain a full-fledged vision. The simplest treatment is a drug called Avestin (an injection in the eye) . Reviews It is possible to evaluate the effectiveness of this method in practice.
With "dry" macular degeneration, medicinal and therapeutic methods can be used. Also for this purpose, patients are prescribed special vitamin remedies.
When the drug "Avestin" is prescribed: the indications
This drug can be prescribed for metastatic colorectal cancer (for example, with tumor lesions of the mammary glands), renal cell tumors, glioblastoma, epithelial ovarian cancer, abdominal cavity, pelvic organs. And, of course, it is a permanent panacea for "wet" macular degeneration and macular degeneration.
In addition, "Avestin" (instructions for use Confirms this fact) is prescribed as an additional method of treatment. For example, it is used together with chemotherapy. Use it and in tandem with other means, for example, with paclitaxel and interferon.
In a word, it is a wonderful drug that can be easily combined with others. However, any of these systems, as a rule, is a doctor. Self-medication in this case is unacceptable. Example instruction:
What is included in the composition?
Since the drug is injected through the most vulnerable shell of the eye, its component is as close to natural as possible. Thus, his instructions refer to the following substances: monohydrate sodium dihydrogen phosphate, trehalose dihydrate, anhydrous sodium hydrogenphosphate, polysorbate and water. In its composition, you can also find bevacizumab and other additional substances.
In what forms is it produced?
"Avestin", as a rule, is sold in a cardboard box wrapped over a glass container with a tight lid. It is a colorless or slightly brownish liquid. It is used as a concentrated solution for infusions or injections. This drug is produced in vials of 100 or 400 mg.
How it works?
Treatment with the drug occurs according to the following principle: the drug-concentrate is diluted with a sodium chloride solution, placed in a syringe. Next, the pre-treated eyeball site is punctured, and the drug is injected through the needle inwards. In this case, it is necessary to have time to introduce the drug "Avestin" (prick in the eye Very carefully) in just a few seconds.
After a 60-minute break, a reaction to the drug is expected. If everything went well, a second injection is performed after the given time. With further positive reactions, the waiting time (between infusions) can be reduced to half an hour.
How is the drug dispensed?
The drug "Avestin" (the equivalent of "Lucentis") should be properly dosed. The standard dosage, calculated for one procedure, is 1.5 mg. A full-fledged course of treatment involves the use of the drug for 3-4 months.
Then the patient goes to a routine examination. And already by its results the attending physician can advise to stop or repeat the entire course anew. In this case, the state of health of the patient will play a huge role in the future plan of action. For example, if a patient experiences visual impairment, the use of the drug will generally resume.
What contraindications exist?
To everyone who uses Avestin!
Contraindications for this drug is. Therefore, before using this inhibitor, be sure to get a doctor's approval and carefully read the instructions. This must be done in order to avoid possible negative consequences.
So, to contra-indications of a preparation it is possible to carry an individual intolerance of any of its components. It is not recommended to apply the medication in case of kidney and liver problems (in case of pathologies and other types of abnormalities). It is strictly forbidden to use the drug for pregnant and lactating women, as well as for minors. According to the instructions, the drug is designed for people ranging from 18 years of age.
Do not prescribe treatment "Avestin" to people who have problems with the eyes are complicated by various kinds of inflammation and suppuration. Carefully take the medicine to the following persons:
- Old age (from 65 years);
- Suffering from thrombophlebitis;
- With cardiac or renal insufficiency;
- With congenital hemorrhagic diathesis.
Than it is possible to replace?
The most suitable for the composition and principle of the drug is "Lucentis". However, unlike Avestin, this medicine has a higher price and is used exclusively to treat various eye disorders. Both medicines are dispensed exclusively by prescription.
What feedback can you hear?
About this drug you can hear completely diverse reviews. Someone helped him, but someone was disappointed. In some, the process of recovery dragged on for a long time. Others complain about a whole list of side effects, which they observed during the period of application of the drug. For example, the most frequent is dysbiosis, acute pain in the eyes, allergic dermatitis, conjunctivitis, disorientation in space, headaches and redness in the vascular region.
Among the reviews you can find those that talk about a senseless waste of money. According to these users, the drug did not help them at all. For this reason, they did not reuse it. Some refer to the fact that after using the medicine their vision has not improved, but it has become worse. They note the appearance of vague images, foreign spots before the eyes, swelling and pain in the area of the injection.