Symptoms of diffuse pancreatic changes: what is it, symptoms and treatment

Echogenicity of the parenchyma of a healthy pancreas on ultrasound is similar to the echogenicity of the liver and spleen. In its structure, iron has a head, body and tail of optimal size. Unfortunately, people are already turning to specialists who already have problems, and on the monitors of diagnostic apparatuses often observe signs of diffuse changes in the pancreas due to its inflammation or other pathology.

On diffusion

The term "diffusion" in Latin means "spreading" or "interaction." From the point of view of physics and chemistry, this is the penetration and interaction of atoms or molecules of one substance with atoms and molecules of another. Studying the phenomenon of diffusion, scientists began to understand the essence of the processes occurring in the human body. This is most often the pancreas. Diffuse changes - what is it?

It is easy to observe this phenomenon. It is enough to add a little ink to the glass with water and see how the substances mix. In anatomy, this phenomenon is associated with the interaction and replacement of some cells by others. This is what is found in the ultrasound study: the cells altered by the pathology are located next to the healthy ones. Symptoms of diffuse changes in the pancreas, as a rule, are local (focal) or mixed (diffuse).

What are the manifestations of diffuse changes in the pancreatic parenchyma?

Pathogenic changes in the gland tissue are most often chronic, and therefore there are no symptoms. But on ultrasound at usual sizes at a gland ehogennost it is raised or increased. In elderly patients suffering from cardiovascular diseases, diabetes mellitus, the death of healthy cells is gradually occurring, they are replaced by connective or adipose tissue.

Also, similar transformations are observed when the blood supply of the enzyme-forming organ, the liver, the functioning of the bile ducts, the violation of endocrine and metabolic processes are disturbed. In what other cases are diffuse changes in the liver and pancreas?

Similar symptomatology is observed in pancreatitis or dystrophic disturbance of the metabolic process. The diagnosis of "pancreatitis" may not be confirmed, and then treatment is not prescribed, and the patient does not recognize DIPZH. As a rule, the spreading changes occur in the glandular tissue. In chronic disease, pathogenic tissue changes are virtually asymptomatic. These are moderate diffuse changes in the pancreas.

The provoking factors

The disease can be provoked by various causes:

1) Imbalance in the diet. Abuse of fatty, floury, salty, sweet and savory products.

2) Predisposition by the genetic line.

3) Stress and nervous overexertion.

4) Narcotic and alcohol dependence.

5) Chronic diseases of the digestive system.

6) Self-medication and unsystematic drug use.

How to treat diffuse pancreatic changes? Consider this below.

Insufficient amounts of insulin in the blood and the detection of glucose in the urine are also provoked by DIP. As a rule, the cause of these changes is pancreatitis, which must be treated. It is also necessary to comply with certain rules of the patient's behavior, compliance with the diet.

The main signs of diffuse pancreatic changes

As a rule, the signs of DI are associated with the underlying disease. Most often, patients complain that they feel heavy in the stomach, they suffer frequent diarrhea or, on the contrary, constipation. In acute pancreatitis, the pressure in the pancreatic duct is often increased, which can cause its deformation. Due to the violation of the enzymatic function, some of the digestive enzymes can pass through the pancreatic parenchyma cells and cause poisoning of the body. In this case, the patient experiences pain on the left under the breastbone, nausea, often accompanied by vomiting. There is a rapid pulse and low blood pressure. This condition, as a rule, requires hospitalization.

The initial stage of chronic pancreatitis is provoked by the appearance of edema and hemorrhages in the gland tissues. Then comes atrophy, the gland decreases in size, the connective tissue proliferates, and the ferment-forming cells cease to produce digestive enzymes. Fibrosis is also accompanied by the displacement of healthy cells of the prostate and replacement of their connective tissue. The production of hormones and enzymes ceases. At the initial stage, the symptoms are meager and often similar to those of pancreatic inflammation. There are moderate diffuse changes in the pancreas.

About Lipomatosis

Replacement of normal cells of the body with fatty tissue is called lipomatosis. Symptomatic DIPH with lipomatosis depends on its volume. With insignificant changes in CI, pathology may not manifest itself, but in more serious cases the body begins to gradually experience a deficiency of hormones and enzymes. The proliferation of lipoid tissue leads to the compression of the parenchyma and, as a consequence, to the disruption of the functioning of the pancreas and the appearance of pain syndrome. These are diffuse changes of the pancreas as lipomatous.

To hollow organs are: stomach, urinary and gallbladder. Organs consisting of parenchyma (glandular tissue): pancreas, spleen, liver, etc. The main function of the parenchyma of the prostate is the production of enzymes and hormones.

With diabetes, chronic pancreatitis or acute pancreatitis, there are often changes.

On ultrasound, there is an increase in the echogenicity of the glandular tissue, this is due to the inflammatory process and when the connective tissue (fibrosis) coarsens, which leads to an increase in density. The cause of this anomaly is an imbalance in the metabolism. Another cause of increased echogenicity is lymphomatosis (replacement of the parenchyma with fat cells).

Puffiness of the gland can occur due to pancreatitis, due to which the density of the parenchyma changes and, as a consequence, the echogenic reaction varies too.

How do diffuse changes in the liver and pancreatic parenchyma affect the organs?

Structure changes

The structure of the parenchyma can be uniform and fine-grained. Slightly increased granularity is also not a big deviation. In aggregate, the increase in granularity indicates the presence of inflammation and dystrophic changes in the gland associated with malnutrition.

A healthy parenchyma of the pancreas resembles a liver echostructure, the same homogeneous and fine-grained. Age-related changes in the echogenicity of the gland structure indicate an evolving lipomatosis, which is often associated with the onset of diabetes. Symptoms of diffuse pancreatic changes can be very informative.

Reactive LMI

This is its secondary changes, a response to pathology in neighboring digestive organs, closely related to it. Especially often DI glands arise because of problems with the liver and biliary tract, since it most closely interacts with these organs. In ultrasound research, the reactive echoes of diffuse pancreatic changes resemble acute pancreatitis, since they are often the secondary consequence.

Fibrotic DIC

Fibrotic MI is a scarring in the gland of connective tissue that propagates through tissue cells. The reasons for this process are often:

1) Metabolic disorders.

2) Alcohol poisoning.

3) Viral lesions.

4) Inflammatory processes.

And the damage caused by the viruses affects the entire hepatobiliary system, not one of the pancreas. On ultrasound, diffuse changes in the pancreas have a high echogenicity and density. The presence of diffusive fibrotic changes may indicate an existing benign tumor of glandular tissue - fibroma, the growth of which can squeeze the gland and cause pain.

Depending on the location of fibroids, there will be different symptoms. For example, when it is in the head of the prostate, the flow of the flow channel is compressed, and a symptom of jaundice appears. If the tumor presses on the duodenum, nausea, vomiting, and other symptoms occur that require differentiation with intestinal obstruction. What are the other echoes of diffuse pancreatic changes?

Dystrophic LPL

There is a replacement of healthy glandular cells with fatty tissues, unable to perform the enzymatic function of the pancreas, which leads to hypofunction of the gland. For lipodystrophy, which occupies less than half the volume of the entire gland, mixed medication is used in conjunction with the diet. If the lesion covers more than half of the organ and its work is disrupted, surgery is indicated. Diffuse changes in the parenchyma of the liver and pancreas in some cases are life-threatening.

In the structure of this secretory organ distinguish three elements: the body, head and tail, having a pear-shaped shape and adjacent to the spleen. Normally its width is 2-3 cm. Through the entire gland an excretory duct about 15 cm long passes. The occlusion of the hepatic vein can lead to the DI of the tail of the prostate, the symptoms of this are that this part is condensed.

Approximately one-fourth of all pancreatic diseases are associated with diffuse changes in the tail. In the case of minor lesions, the tail is treated conservatively. In the case of deep lesions, removal of the tail is indicated, followed by closure of the blood vessels.

How do diffuse changes in the liver and pancreas come about?

Diagnostics

DIPA is determined by ultrasound. Ultrasound reveals the fact that the density and structure of the tissue changes, the foci of inflammation are determined.

But this is not enough to make a diagnosis. To confirm the DI, a biochemical blood test, endoscopy of the gland is performed. It is very important to correctly collect anamnesis in the patient (a survey about the presence of complaints), as well as conduct additional instrumental research and palpation.

The general picture is supplemented by a general analysis of blood, urine, endoscopy of the gastrointestinal tract, coprogram, etc. Pancreatic and glucose enzymes in the blood, as well as an inhibitor with respect to trypsin play an important role.

With the help of ultrasound, the size of the gland and its ducts is determined, neoplasms and compaction are detected. To clarify the diagnosis shown: computed tomography and ERCPG, allowing more accurate identification of the causes of changes in the tissues of the enzyme-forming organ. The most obvious manifestations of diffuse pancreatic changes in the type of lipomatosis.

Prevention

The process of development of MI in the pancreas, liver and other organs can be slowed down. Here are some rules:

1) It is necessary to completely abandon alcohol.

2) Observe the diet, eat in small portions, but often.

3) Minimize the consumption of fatty foods.

4) Discard the canned products.

5) Eat freshly squeezed juices and drink herbal teas.

Do not give up if you are diagnosed with DIP. Just need to pass the necessary research and in the future carefully listen to your body, monitor the health of such important organs as the liver and pancreas. Diffuse changes, what it is and what are the methods of treatment, we considered in the article.