"Sirep" (syrup): instructions for use and reviews

How is Sirep (syrup) used and why is it prescribed? The instructions for use and indications for the use of the suspension will be described later. Also you will learn about whether it is possible to give this drug to children, whether it has side effects, contraindications, etc.

Composition, packaging, description

In what packaging is sold the drug "Sirep" (syrup)? Instructions for the use of medicines are embedded in a pack of cardboard. It also contains a dark plastic bottle, sealed with a screwed plastic cover with a warranty ring.

The preparation in question has an orange color, and also contains an active substance such as fenspiride hydrochloride. In addition, the suspension also contains additional ingredients in the form of methyl parahydroxybenzoate, glycerol, propyl parahydroxybenzoate, potassium sorbate, sodium saccharinate, orange and yellow dye, sucrose, honey aroma, vanilla flavor, citric acid monohydrate and purified water.

Pharmacological properties

How does the drug "Syrress" (syrup) work? The instruction says that the active substance of this drug has an anti-inflammatory effect, and also counteracts bronchoconstriction.

These properties of the drug are the result of the interaction of interrelated mechanisms:

• The anti-inflammatory effect is associated with a decrease in the production of proinflammatory factors. By the way, some of them have a bronchoconstrictive effect. Although such effects are observed only at very high concentrations or doses of the drug.
• The antagonistic activity of the drug occurs at the level of histamine H1 receptors.

Pharmacokinetics

What pharmacokinetic parameters does Syrpus syrup have? Experts say that after taking the suspension inside its maximum concentration is achieved after 6-8 hours.

As for the half-life, it is 12 hours. The active substance of the drug is excreted by the kidneys.

Indications for use

At what diseases is the drug "Sirep" prescribed? Syrup for children and adults is used for rhinopharyngitis, otitis, laryngitis, bronchitis, sinusitis, rhinotraheobronchitis, maintenance therapy for complicated and isolated bronchial asthma, respiratory symptoms in the presence of measles, influenza and pertussis.

Contraindications to taking medicinal syrup

Is there a contraindication to the use of "Sirep" medication? Cough syrup is not prescribed to patients with increased sensitivity to the main substance or additional ingredients that make up its composition. It is also not recommended to give the suspension to children under the age of two.

According to the instructions, this preparation contains sucrose. Therefore, it is not prescribed to people with rare genetic diseases that are associated with the syndrome of poor absorption of galactose-glucose, intolerance to fructose or with an isomaltase-saccharase deficiency.

Medicinal product "Sirep" (syrup): instructions for use

Take this drug should be inside, immediately before meals. Its dosage depends on the type of disease, as well as the patient's age and weight.

Children over the age of two years are usually prescribed 4 mg of the drug for each kg of weight per day.

• Up to 10 kg: 20 ml of syrup or 4 measuring spoons per day (ie 40 mg of fenspiride hydrochloride).
• More than 10 kg: 60 ml of syrup or 12 measuring spoons per day (ie 120 mg of fenspiride hydrochloride). This dose is recommended to be divided into three doses.

How do adolescents and adults get the drug "Sirep" (syrup)? The instruction indicates the following dosages:

• 50-90 ml of syrup or 10-18 measuring spoons per day (ie 100-180 mg of fenspiride hydrochloride). The specified dose of the drug should be divided into several receptions.

To determine a more accurate dose of medication in the package, there is a measuring spoon with a scale of 5 ml, 2.5 ml and 1.25 ml. It should also be noted that 5 ml of the suspension contains 3 g of sucrose (i.e., 0.25 bread units) and 10 mg of fenspiride hydrochloride.

The duration of treatment with this remedy is determined by the treating doctor.

Cases of overdose

When an overdose of the drug "Sirep" in patients can be observed such adverse reactions as nausea, drowsiness, vomiting, agitation and tachycardia.

To eliminate these symptoms, gastric lavage is performed, as well as ECG.

Side effects

What side effects can occur when taking the drug "Sirep". Syrup for children, reviews about which are positive, sometimes causes the following phenomena:

• Cardiac disorders and mild tachycardia (the latter stops after lowering the dosage);
• Vomiting and diarrhea;
• From the side of the digestive tract, the patient often has nausea, gastrointestinal disorders and stomach pain;
• drowsiness;
• Allergic reactions in the form of erythema, Quincke's edema, rash, fixed erythema pigmentosa;
• Because of the presence of para-hydroxybenzoate in the syrup, the patient may develop urticaria;
• Disorders in the work of the nervous system;
• dizziness.

Any occurrence of any of the listed side effects, as well as those that were not included in the list, should be reported immediately to the doctor in charge.

Drug Interactions

Is it possible to combine the preparation "Sirep" (syrup) with other medicines? The instruction does not contain any information on this account. But, taking into account the antihistaminic properties of this drug, one should expect negative reactions during the interaction of the drug in question:

• With barbiturates;
• Other antihistamines, narcotic, analgesic and sedatives, as well as MAO inhibitors and alcohol.

Special recommendations on the use of medicinal syrup

What should the patient be warned about before prescribing him the Siresp product (syrup for children)? The instruction says that for infectious diseases, treatment with this medication is required in conjunction with standard antibiotic therapy.

Due to the content of preservatives such as propyl parahydroxybenzoate and methyl in the suspension, its administration can cause allergic reactions (slow-acting effects are possible).

Patients with diabetes should know that 5 ml of medicinal syrup contains about 3 g of sucrose. This should be taken into account when taking the suspension.

The composition of the preparation "Sirep" includes a dye yellow "sunset sunset". As practice shows, this component often causes allergic reactions in both adults and children (effects with delayed action are possible).

Does the drug "Sirep" affect the patient's ability to manage complex mechanisms and drive vehicles? Studies on this subject have not been conducted.

Analogues and cost of a medicinal product

How can you replace syrup from the cough syrup? The following agents are analogues of this drug: "Erespal", "Eladon", "Erispirus".

As for the price, it is not very high in this suspension. You can buy 150 ml of medicinal syrup for 200-230 rubles.

Patients' comments about the drug "Siresp"

The drug "Siresp" is very popular among patients. This is due primarily to the fact that it has a relatively low cost, and also has a high therapeutic efficiency.

Most of the reviews about this medication are left by parents of young children and adolescents. According to their reports, syrup "Sirep" quickly enough eliminates the unpleasant symptoms of diseases such as sinusitis, rhinopharyngitis, otitis, laryngitis, bronchitis and rhinotraheobronchitis. He also effectively fights against influenza and bronchial asthma.

As for negative reviews, most of them are associated with the appearance of the following adverse reactions: nausea, rash, stomach pain, urticaria.