Remedies for rhinitis. Analogues of "Fliksonase"

The "Fliksonase" agent is a topical preparation. In pharmacies is released at a price of 729 rubles per package. It includes micronized fluticasone propionate, as well as auxiliary substances.

Pharmacokinetics

The agent "Fliksonase" is slightly soluble in water, therefore it has a low absorption with mucous membrane of the nasal passage. As a result, most of it is swallowed. In the systemic blood stream, up to 1% of a single dose of the substance is absorbed. This is the reason for low total absorption of the drug from the nasal cavity and digestive system. 91% of the active substance binds to plasma proteins. The drug "Fliksonase" is output through the liver during metabolism with bile. The drug is available as a nasal spray, 60 doses per vial.

What is the "Fliksonase" analogue?

The price of the drug, it should be said, is relatively high. Therefore, many are looking for what can replace the medicine, while spending less money. Prescribed drugs as a preventive and treatment of allergic rhinitis (year-round, seasonal). Before using any means, a more detailed description of which will be given below, you should shake the bottle. When you open a new one Th vial or in case of interruption of treatment for more than a week it is necessary to check the nebulizer. To do this, you need to click on it, first sending it from yourself. Before using the product, it is necessary to clean the nose, then insert the tip of the vial into one nostril, before closing the other one. After this, perform a single press to spray the substance, inhaling through the nose. At the end, exhale through the mouth. Then repeat the procedure with the second nostril. After using the medication, the tip of the vial should be soaked with a tissue. At least once a week, it is necessary to clean the tip under warm water, removing it from the vial, then dry it and put it back on.

Dosage

Patients 4-12 years of age, the drug is prescribed at 50 μg per nasal cavity once a day. The permissible daily dose is 200 mcg. Patients from 12 years of age are recommended to take 100 μg per nasal passage once a day. After reducing the exacerbation of the disease, the dose can be reduced to 50 mcg. With strong symptoms, it is possible to increase the dose to 400 μg per day. After a short time after relieving the exacerbation of the dose can be reduced. The action of the agent becomes maximum on the 3-4th day of application. For the greatest effect, it is recommended to take the drug regularly.

Side effect. Contraindications

Analogues of "Fliksonase", like the medication itself, have different negative consequences. They are expressed in dryness and irritation of the nasopharynx, nosebleeds, rashes on the skin, headache, bronchospasm. There may be swelling of the face and tongue, an unpleasant aftertaste and smell, nasal congestion, burning. In the case of surgical interventions of the nasal passage, perforation of the septum of the nose is possible. The drug is not recommended for women during pregnancy and breastfeeding, as well as children up to 4 years of age.

"Nazonex" or "Fliksonase" - which is better?

The first drug costs a little more expensive - 790 rubles. But here m Many prefer a more expensive product. In any case, drugs ("Fliksonase" or "Nazonex" or other drugs) should be prescribed by a doctor. Self-medication is not allowed in any case. Medication "Nazonex", in addition to anti-allergic, also has an anti-inflammatory effect. The preparation is produced in the form of a spray with a white suspension. The active component of the agent is mometasone furoate, additional substances - citric monohydrate, dispersed cellulose, sodium citrate dihydrate , glycerol, polysorbate 80, purified water, benzalkonium chloride.

What is safer: "Fliksonase" or "Nazonex"?

Contraindications and side effects of drugs in general are similar. The "Nazonex" agent is not prescribed for tuberculosis, various infections of the nasal mucosa, fungal infections, bacterial infections. It is not recommended to use it after recent operations and various types of nose injuries, with individual drug intolerance, pregnancy and lactation. The drug is allowed to be used from an earlier age (from 2 years) than other analogues of "Fliksonase.

Other medications

Today there are various analogues of "Fliksonase". They have a similar mechanism of action and evidence. Sufficiently popular is the Avamis remedy. It also comes in the form of a nasal spray and has anti-edematous and anti Inflammatory action. In pharmacies is released at a price of 505 rubles. The active ingredient of the drug is fluticasone furoate, 99% of which binds to plasma proteins when used. The remedy is excreted mainly with feces, the metabolism occurs in the liver. The spray is used only for injecting into the nose. Its action begins 7-8 hours after irrigation. To set the correct dosage, the vial must be shaken before the first use and pressed 6 times on the dispenser. The same actions need to be done if the spray has not been used for more than a month. The agent is used as well as other analogues of "Fliksonase" - intranasally. The dosage of the medication depends on the age of the patients. Patients from 12 years of age are prescribed 2 injections once a day. Patients from 6 to 12 years - 1 irrigation per day.

Conclusion

Analogues "Fliksonase", like the drug itself, are similar in their properties and applications. There are only small differences in the price, composition, age categories of patients. However, all the drugs examined direct their action to combat anti-allergenic and anti-inflammatory processes. When choosing the drug "Avamis" or "Fliksonase", as well as any other medication, it is necessary to consult a specialist.