Medicinal product Motilac, instructions for use, contraindications

If there is not enough regular cleansing of the digestive tract, dyspepsia develops. It manifests itself by bloating, hiccough, eructation, heartburn, a feeling of fullness and heaviness in the stomach. During the intake of certain medications, improper diet, vomiting and nausea occur. In such cases, you can not do without the drug "Motilak", the instruction gives a detailed description of this remedy.

Active substance of the drug "Motilak" is domperidone, it enhances the peristalsis of the gastrointestinal tract, has an antiemetic effect, relieves nausea. Absorption of the drug occurs quickly. In the brain there is a center that regulates the digestive tract. The mechanism of the work of the preparation "Motilak" is due to the impact on it, the effect on the production of gastric juice is not observed.

There are several indications for the use of "Motilak", the instruction contains the following list:

- Dyspeptic syndromes associated with delayed gastrointestinal cleansing;

- belching, heartburn, including, accompanied by the release of gastric juice into the oral cavity;

- bloating in combination with soreness in its upper part;

- vomiting, nausea of any origin: organic, functional, infectious. Inadequate reactions of the gastrointestinal tract, arising as a result of therapy with medicinal products, impaired diet, intoxication.

The use of the preparation "Motilac" in pregnancy, in its first trimester, can be considered justified only with the obvious superiority of the need for this therapy for the mother before the potential risk for the child. When breastfeeding there is a small accumulation of domperidone in milk (4 times less than in blood plasma). The effect of the active substance on the newborn during the ingestion of the mother's milk with the mother's milk has not been studied, therefore, the use of the drug during lactation is not recommended.

Hypersensitivity to the active substance is one of the contraindications for taking the drug "Motilak". The instruction also names other contraindications - the presence of prolactinoma, inadmissibility of stimulation of the gastric motility, for example, with bleeding in the gastrointestinal tract, perforation and mechanical obstruction.

Do not prescribe the drug "Motilak" to children under 5 years of age, do not also resort to treatment with this medicine, if the weight of the child did not reach 20 kg.

Disorientation, drowsiness, extrapyramidal reactions are symptoms that are observed in case of an overdose by means of "Motilak", the instruction recommends in such cases treatment with activated charcoal, anticholinergics (for extrapyramidal reactions) used in parkinsonism, antihistamines.

Taking the drug "Motilak", the patient must pay attention to the special instructions contained in the instructions. Caution should be observed patients with liver failure. Bearing in mind the fact that the drug is unchanged in the form of kidneys, do not increase its dosage in renal failure. Antisecretory and antacid drugs should not be taken together with the "Motilac", because in this case its bioavailability decreases. The drug does not affect psychomotor reactions, so there is no contraindication to driving.

Speaking of interaction with other drugs, it is worth noting the following manifestations:

- anticholinergic drugs neutralize the effect of the preparation "Motilak";

- antacids reduce its bioavailability;

- inhibitors of CYP3A4-isoenzyme increase the plasma level of the active substance domperidone;

- the level of digoxin, paracetamol remains unchanged under its influence;

Keep the preparation "Motilak" at a temperature not exceeding 25 ° C, for a maximum of 2 years.