Invisible to the common eye of the Blashko line on the human body

Imperceptible to the naked eye patterns on the human body arise under the influence of exogenous and endogenous negative factors. Pathologies like Blaschko lines are defined. Melanogenesis is manifested by hypopigmentation, refers to diseases of a group of dermatoses. Visible benign formations are of interest to science. Understanding the principle of the appearance of a tumor, you can prevent the appearance of melanoma.

History of skin pathology research

The German researcher of dermatological problems discovered the Blashko line in 1901. They are a pigmentation pattern, similar in structure to all patients. The disease was named after the name of the scientist, whose name is Alfred.

The dermatologist has established an interrelation of occurrence of a pathology with X-chromosomes. On healthy skin, changes are not noticeable at their normal concentration. As a result of chaotic migration of malanoblasts, the formation of the visible region of the pattern occurs. The state of mutated cells depends on the nervous breakdown of the body. However, dermatological problems can be detected with inherent inheritance of the disease.

The main causes of abnormalities in human skin

The following factors determine the formation of the Blashko line on the body:

• Chimerism is often referred to as a condition in which two types of DNA are observed in humans. A different set of genes provokes the formation of pigmentation on the body. Such consequences are found when two different races are incest. The causes of skin pathology is the fusion of a fertilized egg in the early stages of pregnancy.
• Stressful instability of a person - a chaotic pattern is formed.
• Genetics is the introduction of changes in human DNA. The cause of the pathology is the congenital appearance of nevi: depigmented, pigmented, sebaceous, linear verrocus inflammatory.
• Genetic mixing of DNA during embryogenesis - scientists established the structure of human tissues: one set of genes is observed in one cell. Although the origin of the latter comes from a single zygote.

The nature of the appearance of dermatosis

The observer is not familiar with the term "Blaschko lines" - what is that line? Such problems are often found in newborn children, no more than 2% of whom are predisposed to the appearance of pathologies. The structure of DNA already contains the information of the disease. External signs arise as a result of deviations in the endocrinology of the body.

The Blaschko lines are characterized by three cells in the body that are the source of the disease:

• Keratinocytes of the epidermis - acquired pathologies are often observed as a result of chimerism.
• Pigmentary - located in the lower layers of the epidermis.
• Profiling border pigment cells - lead to a change in skin color, passing through the basal membrane into the upper layer of the dermis. This state is observed with the innate nature of melanoma formation.

External signs

In the medical literature, information on the Blaschko line is indicated: that this is a disease of human tissues, which manifests itself in failures in the body during life. The structure of the invisible pattern on the back resembles in part the color of animals: a zebra or a tiger. It can be observed with ultraviolet radiation.

The color of the human skin depends on the pigmentary substance melanin. It is formed in the epidermis of tissues, the basal layer contains melanocytes. Deviations in the process of melanogenesis lead to a change in color that is noticeable visually:

• Hyperpigmentation is a chaotic pattern of dark spots on the skin, distinctly distinguished from the underlying shade of the integument.
• Hypopigmentation - loss of coloration of skin cells, which is expressed by whitish spots. A rare pathology is observed in no more than 1% of newborn children.

An external manifestation of the disease becomes a V-shaped pattern, in the form of curls or undulating lines. It is formed more often on the following parts of the body:

• Back;
• On the side parts;
• Shoulders;
• Head.

Diagnostic problems

The Blaschko line is noticeable when a person is exposed to ultraviolet light, but during the life of a person who rarely undergoes such a survey. To study the state of the body proceed even with the progressing stages of disease. In newborns, light spots of hypopigmentation on the body are difficult to notice. The child acquires pronounced skin changes in a few years.

The state of cells is affected by a set of chromosomes. If it is strikingly different in the neighboring parts of the skin, then there are deviations in the color of the tissues. So hypopigmentation can be manifested by the following conditions:

• Chaotic spots - are interesting to science because of the unevenness of the formations. The picture shows complex figures in the form of strips, chess cells.
• Localized - are manifested by a single spot in a certain area.
• Generalized - can be accompanied by diseases of internal organs.

Why do I need to study drawings on the skin?

Physicians resort to the analysis of the texture of tissues with visible complications on the skin. Here the main indicator is the Blaschko line, the disease is examined for the correct diagnosis. This becomes important with the following dermatological problems:

• Chimerism;
• Mosaicism;
• Deprived;
• Nevus;
• Melanoma.

Complex textures are important only from the research side, for the philistine such an analysis does not lead to definite conclusions about the disease. Scientists intend to disclose the appointment of patterns on the human body. Perhaps, the results of discoveries will help to overcome rare skin diseases.