Detailed instructions for using Novokainamid

In our country, mortality from cardiovascular diseases is one of the leading causes among other reasons. Affects the negligent attitude of people to their health, improper nutrition, addiction to alcohol and smoking, a sedentary lifestyle. Currently, a large number of drugs are produced that not only help to cope with heart disease, but also prevent their occurrence. One such drug is Novokainamid, the instructions for use will be discussed later.

Structure of the preparation

Manufacturers produce "Novokainamid" in two forms: tablets and solution for injections.

The active component of each form is procainamide, which in tablets contains 250 mg in each, and in a solution of 100 mg. As auxiliary substances in tablets contain: calcium stearate, starch and lactose.

If you take a solution of the drug, the additional components are water for injection and sodium disulfide.

Pharmacodynamics of Novokainamid

If we talk about the drug Novokainamid, the instruction description contains the following: refers to antiarrhythmic medicines. Prokainamide, which is part of the drug as the main active substance, has a good membrane stabilizing effect.

The mechanism of its action is based on inhibition of the incoming channel of sodium ions, as well as a decrease in the rate of depolarization in the zero phase. "Novokainamid" inhibits conduction, lowers the excitability of the heart muscle in the ventricles and atria.

Procainamide is also able to have a vasodilating and vagolytic effect, which leads to a decrease in blood pressure and the appearance of tachycardia.

When the use of the drug is indicated

Cardiac drugs are serious medicines, which in no case can not be taken without the appointment of a doctor. Only a specialist, given the diagnosis and characteristics of the patient's body, can prescribe the right drug. The indications for Novokainamid are as follows:

  • The patient is worried about tachycardia.
  • There is a ventricular extrasystole.
  • Atrial flutter.
  • Ventricular arrhythmia.
  • Atrial extrasystole.
  • Syndrome WPW.
  • Atrial fibrillation.
  • Violation of the heart rate.

All these diagnoses are established only after careful examination of the patient.

Contraindications for use

The instruction for the application of Novokainamid also contains information on contraindications to the use of this medication. The medication is not indicated when:

  • Arrhythmia, which is caused by an overdose of cardiac glycosides.
  • AB-blockade of 2 and 3 degrees.
  • If there is leukopenia.
  • Hypersensitivity to the components of the drug.
  • If there are abnormalities in the liver or kidneys.
  • In the presence of myasthenia gravis.
  • Myocardial infarction is also a contraindication to the use of the drug.
  • High blood pressure.
  • Atherosclerosis.
  • Bronchial asthma.
  • The instruction on the application of Novokainamid warns of the careful prescribing of the drug for the elderly.
  • Cardiogenic shock.
  • Systemic lupus erythematosus, including this disease in the anamnesis.
  • During the period of breastfeeding.
  • It is undesirable to appoint Novokainamid to children under 18 years of age, the instructions for use do not contain information about the efficacy and safety of the drug at this age.

Treatment schedule and dosage

The drug can be taken orally in the form of tablets, injected intravenously or intramuscularly.

If assigned as a Novocainamide solution, the instructions for use in ampoules contain detailed information on the application.

For intravenous administration, dissolve 100-500 mg of procainamide in saline and inject slowly, at a rate of not more than 50 mg per minute. During the introduction, it is necessary to control blood pressure.

There are situations where repeated administration of the same amount of the drug is required to achieve the desired effect. In order to prevent an attack of arrhythmia, the infusion is carried out at a rate of 2-6 mg per minute.

After the attack is stopped, it is possible to maintain the effect by intramuscular injection of the drug in an amount of 0.5-1 gram.

As a remedy "Novokainamid" intramuscularly administered at 50 mg per kg of patient weight per day, this dose should be divided into several injections.

The maximum dose for adults with intravenous or intramuscular injection is 1 gram per injection or 3 grams per day.

For Novokainamid, instructions for the use of the pill at the beginning of therapy recommend taking one hour before meals or 2 hours after eating. The tablet should not be chewed, but with plenty of water.

If there are no side effects, then you can go to the necessary therapeutic dose, it can be from one to three tablets. For maintenance therapy, the doctor appoints one tablet every 6 hours.

Undesirable manifestations

If a Novokainamide medication is prescribed, the instructions for use should be well understood. In it, you can find information about the occurrence of side effects in the treatment of this drug. These include:

  1. Ataxia.
  2. Psychotic reactions.
  3. Appearance of seizures.
  4. Dizziness.
  5. In serious cases, it comes down to hallucinations.
  6. Myasthenia gravis.
  7. There are frequent headaches.
  8. The patient begins to suffer from depression.
  9. There are cases of manifestation of oppression of bone marrow hematopoiesis.
  10. The taste is broken.
  11. Anemia is diagnosed.
  12. There is a ventricular tachycardia.
  13. Blood pressure is reduced.
  14. Intracardiac conduction is disturbed.

If therapy "Novokainamidom" is appointed for a long period, then it can develop a lupus erythematosus. Some patients also note that during treatment with the drug can attack microbial infections and there is a longer healing of wounds.

Symptoms of drug overdose

The article examined Novokainamide medication, instruction, description, the photo below shows what symptoms of drug overdose may occur during treatment.

It can be characterized by the following manifestations:

  • Severe dizziness.
  • There is drowsiness.
  • There may be a fainting condition.
  • Confusion of consciousness.
  • Vomiting.
  • Heart palpitations are increasing.
  • Paroxysmal tachycardia is observed .
  • The patient loses his appetite.
  • Diarrhea begins.
  • The blood pressure drops.
  • Collapse.

To provide first aid, it is necessary to introduce the patient "Phenylephrine" and "Norepinephrine" if the blood pressure has fallen. Effective means of help are gastric lavage, hemodialysis.

Interaction of the drug with other drugs

The instruction on the application of Novokainamid contains information on the interaction of the drug with other drugs. It is necessary to know before proceeding with the drug therapy that:

  • The drug enhances the effect of taking muscle relaxants, holinoblokatorov.
  • The effect of antihypertensive drugs is increasing.
  • If you take both antihistamines at the same time, the atropine-like effect is enhanced.
  • If the "Pimozode" is received simultaneously, then an extension of the QT interval can be seen on the ECG.
  • The drug intensifies the manifestation of side effects when taking "Tozilata Brethilia".
  • The likelihood of arrhythmogenic effect increases if antiarrhythmics are simultaneously prescribed.
  • Admission joint "Cimetidine" increases the half-life of "Novokainamid" and reduces renal clearance.

Before prescribing the drug, the doctor must necessarily ask what medications the patient takes to take into account all possible interactions.

Important instructions when taking Novokainamid

It has already been said that it is necessary to take the medication tablets on an empty stomach or a couple of hours after eating. Drink with milk or water. If injections are prescribed, the solution must be diluted before administration.

During the treatment period, Novokainamid needs to constantly monitor blood pressure, the level of leukocytes in the blood, and do an ECG.

After the treatment, many patients register an elevated titer level of antinuclear antibodies. If long-term use of the drug after surgery on the heart, it is possible to develop leukopenia.

In elderly patients there is a risk of developing hypotension, so it is necessary to constantly keep the pressure under control. Particular care should be taken when prescribing this drug to children. Dosage should be carefully calculated.

Reception "Novokainamida" affects the concentration of attention, so you should refrain from driving the car during therapy with this drug. Also, be cautious in those activities where increased attention and concentration is required to avoid injury.

Taking the drug during pregnancy

The instruction on the use of Novokainamid warns that the use of the drug during pregnancy can lead to a decrease in blood pressure, which, in turn, often ends with utero-placental insufficiency.

Analogs and synonyms of the drug

Analogues of any drug are drugs that have the same effect on the body. If you consider the drug "Novokainamid" (description, analogue, photo), then he has several such drugs:

  • "Aymalin" in the form of concentrate for solution preparation.
  • "Aimalin" in the form of tablets.
  • "Quinidine sulfate".
  • Hinipec tablets.

Despite the fact that all the analogues have a similar effect, all the same, you should not prescribe yourself a medicine. The doctor, taking into account the features of the course of the disease, as well as the patient's organism, appoints the drug that will prove to be more effective.

In addition to analogues, there are also synonyms with Novokainamid, these are preparations with the same active substance. To such it is possible to carry:

  • Novokainamid-Ferein is a solution for intravenous and intramuscular injections.
  • Procaninamide-Eskom is also a solution for injections.

With any disease, you can always pick up analogs and synonyms of the drug that the doctor prescribed. Many patients are guided by the price and try to purchase cheaper analogs, but it must be remembered that the active substance can be the same, but a joint combination with other components can give a completely different effect. Drink to the advice of specialists, and do not self-medicate, so as not to further damage your health.

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