Application, instructions, references and analogue of "Lokrena"

Hypertensive disease is very common in the world. This is a rather insidious disease, which at the initial stages is difficult to identify. Therefore, after 40 years, it is worth regularly monitoring the performance indicators. If the results are too high, then you need to consult a therapist. The sooner you start treatment, the faster you can defeat the disease.

Modern drugs are highly effective. This is a group of adrenoblockers. Tablets very gently reduce the pressure and do not harm the body. Today, the drug "Lokren" is very popular among therapists. Directions for use, analogues, correct dosage - all this information will be presented below.

Composition and form of the drug

The tablets "Lokren" are white, slightly convex, on one side there is a marking with the inscription EK20. With the help of such a titer, the drug can easily be distinguished from a counterfeit. The tablets are coated with a thin coating. The main component in the composition of tablets is betaxolol hydrochloride in a dose of 20 mg. Auxiliary components of the drug are lactose monohydrate, cellulose microscopic, carboxymethyl starch sodium.

The shell in the composition has gipromilose, macrogol, titanium dioxide. Tablets are produced in blisters, 14 in each. Any analogue of "Lokren" will have a similar composition and indications for use.

Effect of the drug on the body

Tablets belong to the group of beta-blockers. They are considered selective blockers of the first series. Betaxolol, which is part of the drug, has a cardioselective beta-adrenoblocking effect, is characterized by a lack of agonist activity, and serves as a weak membrane stabilizer. Thanks to this medicine, the heart rate is reduced in the period of rest and physical activity. The main effect is a decrease in blood pressure in a calm state and under load.

When using the medicine, tachycardia passes, the load on the heart decreases, peripheral circulation is normalized. The antihypertensive effect of betaxolol does not decrease with prolonged use. When administered to one dose of the pill, a therapeutic effect occurs within three hours and lasts for a day. A stable result is achieved at a course of treatment. Such actions have an "Lokren" tablet on the body. Analogues of the drug also normalize arterial indices with proper use.

Pharmacokinetics

Upon ingestion, the drug dissolves very quickly and is absorbed 100% from the stomach. The maximum action in plasma is achieved in two hours. The drug binds to blood proteins by 50%. Betaxolol in the liver forms inactive metabolites. Almost 80% of the active ingredient is excreted by the kidneys in the form of metabolites. 20% out of the body in an unchanged form.

Fast enough to achieve a positive therapeutic effect, if correctly taken tablets "Lokren." The instruction for use contains all the necessary information.

Indications and contraindications

The reason for prescribing the drug is hypertension. The agent can be taken alone or in combination with other medications to reduce pressure. Tablets are prescribed for the prevention of angina pectoris attacks.

Contraindications to treatment with the drug are considered severe forms of bronchial asthma and chronic bronchitis, acute heart failure. You can not take medicine for pronounced phenomena of bradycardia, severe forms of Raynaud's disease and violation of peripheral circulation. There are age limits. Medication is not prescribed to minors.

It is not recommended to drink tablets in case of renal and hepatic insufficiency. During pregnancy and lactation, the remedy can only be used if the potential benefit to the mother exceeds the possible harm to the baby.

Before starting treatment, it is worthwhile to carefully study the instructions for using Lokren. Feedback from specialists shows that side effects occur most often in those patients who do not adhere to the recommendations.

Dosage

The drug should be washed down with a lot of liquid. The medicine can not be chewed. Begin the treatment with a half tablet (10 mg). If the positive therapeutic effect does not occur within two weeks, it is necessary to increase the dosage. The maximum daily allowance can not exceed 40 mg.

Many doctors do not recommend their patients to drink more than one tablet a day. With a bad decrease in pressure, one more antihypertensive drug should be added to the treatment. Patients with severe renal failure should begin taking the drug with a dose of 5 mg. Gradually the daily rate increases. Be sure to read the instructions for use before using Lokren.

Overdose

In case of an overdose of tablets, dizziness, severe pressure decrease, cyanosis of the fingers and nails, bradycardia, a pre-stupor condition can be observed. Also develop symptoms such as bronchospasm and heart failure.

Treatment for an overdose consists in rinsing the stomach. It is recommended to give the patient a drink of adsorbent and to connect infusion therapy. With a marked decrease in pressure, it is necessary to drip Dopamine and introduce Atropine. It is necessary to add cardiac glycosides and antispasmodics. In a severe case, the introduction of blood substitutes and plasma is indicated. Any analogue of "Lokren" should be taken, adhering to the dosage appointed by the doctor.

Side effects

When treatment with the drug may begin an allergic reaction. It manifests itself in the form of a rash on the skin and itching. There are also reactions from the nervous system, which are manifested by dizziness, headache, asthenia, insomnia, nightmares, paresthesia. Side effects include decreased vision and decreased intracranial pressure. During the reception of tablets, pain in the abdomen, nausea, vomiting are often observed. Blood counts may change and leukopenia develop. In men, taking medication often causes impotence. With caution, you need to prescribe pills in old age.

It should be stored at room temperature in a dark place inaccessible to babies, the drug "Lokren". Analogs are used under the same conditions.

The analogue of "Lockren" in Russia is the preparation "Betaxolol"

How to choose a quality replacement drug? What if there was no "Lokren" in the pharmacy? Analogues of the drug will always be able to recommend a doctor. The "Betaxolol" remedy is popular. This is a cardioselective beta-blocker, which is used to lower blood pressure and angina attacks. After ingestion, it is completely cleaved in the stomach. The maximum effect is achieved in plasma for three hours. The medicine is excreted by the kidneys in the form of metabolites that are formed in the liver.

The drug perfectly lowers the intraocular pressure, if you use a solution in the form of drops for the eyes.

The medicine is used once a day at a dosage of 20 mg. The medication can be taken alone or as part of a complex therapy. It is not recommended to take the drug during pregnancy and lactation. The medicine in rare cases causes side effects in the form of a rash and burning on the skin. There may also be dizziness and nausea, as with Lokren tablets. Analogues Russian have the same indications and contraindications.

The preparation "Betak"

The drug belongs to the first-line beta-blockers. Tablets of white color. Each dose contains 20 mg of betaxolol hydrochloride. A medication can only be prescribed by a doctor. The drug helps to normalize blood pressure, reduce the heart rate at rest and under physical exertion, normalizes peripheral circulation and reduces attacks of angina.

It is not recommended to prescribe medication for kidney and liver pathologies. During pregnancy and feeding, the drug is not allowed. The agent can cause an allergic reaction and small deviations in the work of the nervous, digestive systems. Caution should be given to people in old age and with increased sensitivity to the components of tablets. This analogue of "Lokrena" may well replace the original import.

Reviews

Experts say about beta-blockers positively. In a short period, you can normalize the pressure and reduce left ventricular hypertrophy. These drugs are well tolerated by patients and do not affect the work of other organs and systems. Any analog of Lokren will show a positive effect if used in accordance with the instructions.