HealthPreparations

The drug "Valdoksan", instructions for use

The drug "Valdoksan", the instruction indicates, is released in the form of tablets, in each of them is 25 mg of the active substance - agomelatine. The drug belongs to the clinical and pharmacological group of antidepressants.

Pharmacological action is based on the ability of agomelatine to intensively release dopamine and norepinephrine directly in the cerebral cortex. The amount of extracellular seratonin does not change.

The medicine "Valdoksan" improves the condition of patients suffering from chronic stress of moderate severity, a sense of desperation and helplessness. Normalizes desynchronization of circadian rhythms.

Tablets "Valdoksan" (analogues for the active substance are represented by the preparations "Agomelatin" and "Melitor")   Contributes to the restoration of the natural structure of sleep, the formation of melatonin and in addition to lowering body temperature. A stable positive dynamics is observed in patients with prolonged depression after 6, 8 weeks of taking the drug with a daily dosage of 25 mg to 50 mg.

In clinical trials, a stable therapeutic outcome was established in patients with complex depressive disorders who took antidepressant Valdoxan in recommended doses.

The instruction indicates that this remedy does not violate the memory function, concentration of attention, at a dosage of 25 mg increases the phase of slow sleep, without changing the number of phases of fast sleep, their duration. Additionally, the active substance contributes to the treatment of disorders of the sexual sphere, normalizing the phase of excitement and orgasm. The weight of the patients did not increase, the blood pressure remained unchanged, the medication was not affected by the heart rate. After the withdrawal of agomelatine, a feeling of addiction does not arise.

The medicine "Valdoksan", instructions, testimonies

The doctor prescribes a drug to treat major depressive disorders in adults.

Dosing

Tablets are intended for oral use 1 time before going to bed. At the beginning of the treatment the doctor recommends taking 1 tablet of the medicine "Valdoksan", which, in terms of the active substance, is 25 mg of agomelatine. If the clinical picture does not improve after two weeks, the dose is increased to 2 tablets, which means 50 mg of the drug.

During the therapy, it is necessary to monitor the work of the liver. The drug is intended for a long course of treatment, lasting up to 6 months, until all symptoms of a depressive condition stop.

Side effect of the medicine "Valdoksan"

The difficulty in determining the side effects of drug treatment is that it is difficult to distinguish the signs of the disease and the negative consequences of therapy. The most common side effects that occur during treatment are nausea and dizziness, which quickly go away. In the vast majority of cases, discontinuation is not required.

Among the disorders in the work of the nervous system are data on headache, drowsiness, insomnia, migraine, paresthesia.

Among mental disorders, there are data on the occurrence of anxiety, agitation, mania, suicidal behavior, although such symptoms may be a manifestation of the disease.

Among the disorders in the digestive system are data on the occurrence of nausea, diarrhea, constipation, abdominal pain.

Possible violations in the hepatobiliary system.

Among other abnormalities in the body there are data on the occurrence of sweating, eczema, itching, rashes, visual disturbances, back pain and general fatigue.

Contraindications

You can not in some cases prescribe a medicine "Valdoksan." The instruction contains a list of conditions in which the use of this medication is contraindicated:

  • With hepatic insufficiency;
  • In combination with strong inhibitors of the isoenzyme CYP1A2;
  • For children under the age of 18;
  • For patients with lactose intolerance;
  • With increased sensitivity to one of the components of the drug.

The drug "Valdoksan" and alcohol are incompatible. When prescribing the drug, elderly patients should be extremely cautious.

Similar articles

 

 

 

 

Trending Now

 

 

 

 

Newest

Copyright © 2018 en.birmiss.com. Theme powered by WordPress.