Drug 'Tobrex' (eye drops). Instructions

The drug "Tobrex" is a drug used in the treatment of eye diseases (infectious genesis) and its appendages (conjunctivitis, blepharitis, blepharoconjunctivitis, keratoconjunctivitis, iridocyclitis, keratitis). The form of release - eye drops.

The drug "Tobrex" (eye drops). Instruction: composition, pharmacological properties

The composition of the drug is tobramycin, which is an active substance. Auxiliary components: benzododecinium bromide, xanthan gum, trometamol, mannitol, polysorbate 80, boric acid, sulfuric acid, sodium hydroxide, purified water.

With external application, the drug has virtually no systemic effect. It is quickly released into the urine by means of glomerular filtration in an almost unchanged form. Half-life is two hours. The components of the drug are not able to bind to protein molecules of the blood. Bioavailability with internal admission is less than one percent.

Tobramycin is an antibiotic with a wide spectrum of action, it is part of the group of aminoglycosides. At low concentrations, it exhibits a pronounced bacteriostatic effect: it disrupts the synthesis of protein molecules by blocking the 30S subunits of the ribosomes. The use of high doses changes the properties of the drug: it disrupts the functions of membranes (cytoplasmic), causes death of microbes. The drug has activity against staphylococci (resistant to the action of penicillin), streptococci, Neisseria, moraxell, proteas.

The drug "Tobrex" (eye drops). Instruction: method of application, dosage

In infectious diseases of the eyes, instillations of one drop of the drug into the affected organ are applied twice during the day. The period of therapy reaches one week. In acute infectious processes, the dosage is one drop of drug in the affected eye four times a day. Then the amount of the drug used gradually decreases, depending on the effectiveness of the therapy. The period of therapy in this case reaches ten days. The drug "Tobrex" (eye drops) for children is absolutely safe. For them, the necessary dose is selected individually, depending on the type of disease, the intensity of its symptoms. Also prescribed medicine "Tobrex" (eye drops) for newborn babies.

The drug "Tobrex" (eye drops). Instruction: side effects, contraindications, drug interactions

Use of the medication can cause the following side effects: blurred vision, itching, transient discomfort, irritation, eyelid swelling, conjunctival erythema.

Hypersensitivity to the components is a contraindication to the use of the drug.

Prolonged use of the drug can cause the growth of microorganisms that will be resistant to its effects. It is necessary to sow after the termination of therapy in case of unsatisfactory clinical results. When administered simultaneously with other antibacterial agents of the aminoglycoside series, there may be an increase in adverse symptoms (ototoxic, nephrotoxic, hemolysis, mineral metabolism). When using the drug with other eye drops, it is necessary to observe a break between instillations (fifteen minutes).

The drug "Tobrex" (eye drops). Instruction: special instructions, overdose

During pregnancy, the drug should be used only in exceptional cases. During the lactation period, this medication should not be used (especially in the case of prolonged treatment).

With topical application, the likelihood of overdose is very low. In the occurrence of such cases, it is necessary to rinse the eyes thoroughly with water (preferably warm).