Choline Alphoscerate: instruction manual, reviews and analogues

Choline alphoscerate is an active drug component that is found in many medical products. About what properties this substance has, for what it is shown and what preparations it includes, you will learn from the materials of the article.

Where is the choline alphoscerate?

Instructions for the use of those medicines that include the presented component are available in each package along with the medication.

The most well-known and widely used medicines with such an active substance are the following drugs:

• "Glazer".
• "Gliatilin".
• "Cerepro".
• "Glycerylphosphorylcholine hydrate."
• "Cereton".
• "Holilitil" and others.

Existing Release Forms

Preparations with such an active substance as choline alphoscerate, which are mostly positive, are issued in the form of capsules and injectable solutions. As a rule, they go on sale in cardboard packages or in small plastic jars.

pharmachologic effect

Choline alphoscerate excites the central cholinergic receptors. Entering the human body, such an active substance breaks down into choline and glycerophosphate.

The presented medicinal component provides a complete formation of phosphatidylcholine. In addition, it significantly improves the plasticity and function of receptors, neuronal membranes, and also activates cerebral blood flow, stimulating cholinergic neurotransmission, the metabolism of the nervous system and the reticular formation.

It should also be noted that choline alphoscerate greatly improves the concentration of attention, the ability to memorize and further reproduce information, significantly increases mood, mental activity, and also removes negative emotions, including apathy, and optimizes cognitive responses.

In cases of craniocerebral trauma, this substance normalizes the blood flow in the affected area and the bioelectrical activity of the brain. In addition, this component of drugs helps to suppress neurological symptoms.

Pharmacokinetics

After ingestion, the absorption of this component is about 88%. Choline alphoscerate quite easily passes through the blood-brain barrier. It should also be noted that this substance accumulates in the brain, lungs and liver. Its level in the central nervous system reaches about 45% of the blood plasma content.

About 86% of the choline of the alphosherate is excreted via the lungs in the form of carbon dioxide, and the remainder - through the kidneys and intestines (approximately 14%). This substance does not have teratogenic and mutagenic effects, and does not affect the human reproductive system in any way.

Indications for use

Why is the patient prescribed choline alphoscerate? Analogues of such a drug and the drug itself are used when:

• Acute period of craniocerebral trauma;
• Discirculatory encephalopathy;
• Dementia (Alzheimer's type, senile or mixed forms);
• Hauge Huntington ;
• During the recovery period of ischemic stroke;
• Memory impairments;
• Functional disorders of the central nervous system;
• Confusion of consciousness;
• Reducing initiative, concentration and motivation;
• Disorientation;
• Senile pseudomelanchy.

Choline Alphoscerate: Instruction

Take medications (capsules) that contain such an active substance, should be inside just before the meal. As a rule, such funds are prescribed by doctors in a given dosage depending on the existing disease. But, according to the enclosed instructions, choline alphoscerate must be taken three times a day for 400 mg. The duration of such therapy is usually about 4-6 months.

If the patient has an acute condition, then the presented component is slowly administered intravenously or intramuscularly. In this case, the dosage of the injection solution is 1 g per day.

If after using the drug in the patient appears severe nausea, then the dose should be reduced by 1.5 or 2 times.

Contraindications for use

Use drugs that contain the presented component, is not recommended for hypersensitivity to it. In addition, choline alphoscerate is strictly prohibited for pregnant women and nursing mothers.

Possible side effects

According to reviews, drugs with the active substance of choline alfoscerate almost never cause any side effects. Occasionally, patients may experience a strong or moderate feeling of nausea. As stated above, in such cases, you should either reduce the dosage, or completely cancel the drug.

An overdose of the drug

If the drug substance choline alphoscerate is uncontrolled, the patient may experience an overdose. As a rule, a patient in such situations feels a strong feeling of nausea, which results in vomiting, and allergic reactions (rash, itching of the skin, etc.) can occur.

Drug Interactions

To date, no interaction of this substance with other medicinal components has been identified.

Price of preparations

The cost of medicines that contain the active substance of choline alphoscerate is significantly different. Consider the price category of each drug in more detail:

• "Glazer" medication. For three ampoules of this remedy you will have to pay about 260-270 Russian rubles.
• The drug "Gliatilin". The price of 14 capsules of this medicine is about 740-760 rubles. If you need to buy a medicine in ampoules, then for three pieces you will be asked about 570 rubles.
• The medicine "Cerepro". Such a drug in capsules is sold for 500 rubles (14 pieces). If you need a drug in ampoules, then for three pieces you will have to pay about 400 rubles.
• Means "Tsereton". Ampules of this drug can be purchased for 280-300 rubles (3 pieces).
• Medication "Holilitil". This drug (ampoules) is sold in pharmacy chains for 370-380 rubles (3 jokes).