Anaprilin instructions for use.

The drug Anaprilinum (Anaprilinum) is a drug for lowering blood pressure.

Pharmacokinetics of the preparation "Anaprilin" instructions for use describes as follows:

This drug increases the ability of the uterus to contract, the motor and secretory activity of the gastrointestinal tract and the tone of the muscles of the bronchi. A blood pressure is reduced, as is the need for oxygen in the muscles of the heart. Absorbed it very quickly, and quickly it is eliminated from the body. The highest concentration of this drug in the plasma is achieved after one - one and a half hours from the time it was taken. The drug is able to penetrate the placental and blood-brain barrier and even into breast milk. The half-life of Anaprilin occurs in three to five hours, with long-term use it can last up to twelve hours. It is derived mainly through the kidneys in the form of metabolites and not more than one percent in unchanged form.

For the "Anaprilin" medication, the indications for its use are the following:

IHD, arterial hypertension, various forms of angina pectoris, various arrhythmias, for example, ciliary, sinus and supraventricular tachycardias, as well as tachycardias with thyrotoxicosis. It is also used for myocardial infarction, essential tremor, NDC, prolapse of mitral cardiac valve, hypertrophic cardioopathy. "Anaprilin" is included in the list of drugs used in combined therapy of pheochromocytoma and withdrawal syndrome.

The method of application of the preparation "Anaprilin" instructions for use describes this:

It is prescribed inside for ten to thirty minutes before eating, after taking a large amount of water to drink. The initial dose of the drug is ten milligrams. If the tolerance of Anaprilin is good, the dosage will gradually increase by twenty milligrams a day, until it reaches eighty to one hundred milligrams, divided into four doses. If the effect is not sufficient, the increase continues to one hundred and sixty to one hundred and eighty milligrams, sometimes up to three hundred, divided into four to six receptions. With cardiovascular pathologies, the course of treatment lasts from three to four weeks. Repeat the course if necessary, after one to two months. In patients with IHD, arrhythmias and angina, the treatment lasts longer. With a long period of use, cancellation syndrome is possible , consisting in aggravation of an anginal attack, a decrease in tolerance to physical exertion and even bronchospasm.

For the drug "Anaprilin" side effects in the instructions described are:

Vomiting, nausea, epigastric pain, ischemic colitis, diarrhea, impaired liver function, arterial hypotension, dizziness, headache, drowsiness or insomnia, nightmares, depression, anxiety, dyspnea, cough, laryngo- and bronchospasm, exacerbation of psoriasis, alopecia, Urticaria, itching.

For the preparation "Anaprilin" the instruction for use gives such a list of contraindications:

Increased susceptibility to drug components, bradycardia below fifty beats per minute, complete or even partial atrioventricular block, weak sinus node syndrome, Prinzmetall angina, arterial hypotension, severe bronchial asthma, diabetes mellitus, with caution apply to patients suffering from spastic colitis. Pregnant women and nursing mothers, as well as children under the age of one, the drug is contraindicated as well.

Interaction with other medications of the drug "Anaprilin" instructions for use describes this:

Any other medications should be notified by your doctor. Hypotensive properties of the drug are increased when taking other antihypertensive, hydralysin, sympatholytics, monoamine oxidase inhibitors. Weaken the effect of the use of this drug estrogen, glucocorticosteroids, non-steroidal anti-inflammatory drugs.

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