The drug 'Flukostat'. Analogues. Indications, side effects.

The drug "Flucostat" (analogues "Diflucan", "Mikoflukan", "Flukonorm", etc.) - a drug that has an antifungal effect; A powerful inhibitor of the synthesis of sterols in fungal cells. Is a representative of a group of triazole antifungal agents. The active substance of the drug "Flucostat" is fluconazole. It is active against various pathogens of opportunistic mycoses, including those caused by Cryptococcus neoformans, Trichophyton spp., Candida spp and Microsporum spp.

Pharmacokinetics

After taking the drug "Flucostat" inside its active substance fluconazole begins to be absorbed efficiently and penetrate into all biological fluids of the human body. It is mainly excreted by the kidneys, about 80 percent of the administered dose remains unchanged in the urine.

Indications for the use of the drug "Flucostat"

In the form of a solution: cryptococcosis, generalized candidiasis, candidomas of the mucous membranes of the pharynx, oral cavity and esophagus, candiduria, bronchopulmonary infections, vaginal candidiasis (in acute or chronic stage), prevention of fungal infections.

In the form of capsules: cryptococcosis, endemic mycoses are deep, mycosis of the skin of the feet, areas of inguinal, body; Lichen cutaneous, skin lesions candida, candidiasis of the genitals, candidiasis of the mucous esophagus, pharynx and mouth, generalized candidiasis.

The drug "Flucostat". Analogues

It is worth considering that asking the question: "Which drug to choose," Flukostat "or" Fluconazole "?", You waste time, because the latter is the active substance of the medicine we are considering. What else means contain in its composition the same active substance?

Structural analogs of the preparation Flucostat according to the active substance

The drug "Diflucan" (USA) is an antifungal agent. In addition to fluconazole it contains auxiliary substances such as corn starch, lactose, colloidal silicon dioxide, magnesium stearate, sodium lauryl sulfate. Many women think about what is best - "Flukostat" or "Diflucan". And most of them tend to the first, as it is domestic production and, accordingly, cheaper. However, in the treatment of fungal diseases, you should not prescribe yourself this medication. This should be done by the doctor, based on the analysis.

In addition to the above-described preparation, analogs can be used in place of the drug Flucostat: preparations Vero-Flukonazol, Diflazon, Disorel-Sanovel, Medoflukon, Mikonil, Mycosyst, Mycomomax, , "Prokanazol", "Nofung", "Fangiflu", "Flukozid", "Flukozan", "Flukomabol", "Flukonazol Hexal", "Flukomycid SEDIKO", "Flukonazol-Teva", "Fluconazole STADA", Flukoral, Flukonorm, Forkan, Flukorem, Fungolon, Ciskan.

Is it possible to use the preparation Flucostat, analogues with the same active substance during pregnancy and lactation?

The use of the drug "Flucostat" during pregnancy or lactation is possible only in the case of fungal infections that carry a potential threat to the life of a woman. The expected benefit of the drug should exceed the risk for the future of the child.

Due to the fact that the active substance of the drug "Flucostat" is allocated together with breast milk in large doses, it is recommended not to prescribe it during lactation.

Side effects

The drug "Flucostat", its analogs have the same side effects. This is severe nausea and vomiting, pain in the epigastric region, flatulence, diarrhea, headache, dizziness, agranulocytosis, thrombocytopenia, leukopenia, seizures, ventricular flutter, skin rash, erythema exudative malignant, epidermal toxic necrolysis, anaphylactoid reactions , hypokalemia Lowering the concentration of potassium ions), disruption of the kidneys, alopecia (that is, loss of hair).