Ibuprofen (400 mg): instructions for use, description and reviews

Pain is a defensive reaction of the body and a signal to a person that, most likely, something went wrong inside. But at times it is unbearable to tolerate, and besides often it is not necessary. There are many modern drugs that allow you to quickly stop painful attacks. One of them is "Ibuprofen" (400 mg), the instruction for its use recommends taking it for the removal of discomfort in a variety of diseases.

general information

There is a large class of drugs that belong to non-steroidal anti-inflammatory drugs. They eliminate pain and have antipyretic effect. Also, these drugs reduce the severity of the inflammatory process, and the effect of them is quite fast. One of these drugs is Ibuprofen (400 mg). Instructions for use recommend taking it for pain of different nature and elevated body temperature.

It refers to high-speed drugs that relieve symptoms, but, unfortunately, do not eliminate the causes of the disease. Therefore, most often, "Ibuprofen" is part of the complex therapy of various diseases. It allows a person to transfer the process of recovery much easier due to the fact that the clinical picture against the background of his admission becomes less pronounced. Parallel with this, etiotropic treatment is appointed, that is, one that affects the true nature of the disease.

Forms and composition

The first thing that catches your eye when you open the packaging medicine "Ibuprofen" (400 mg) - instructions for use. The formulation is as follows:

• The active ingredient is ibuprofen;
• Additional components (may vary depending on the manufacturer) - silicon dioxide, corn starch, magnesium stearate, titanium dioxide, talc, sodium carboxymethyl starch, povidone K30, macrogol 4000, hypromellose, microcrystalline cellulose.

Each tablet has a special feature, which makes it possible to divide the medicine into 2 equal halves. This is very convenient in cases when it is necessary to simultaneously take, say, 200 or 600 mg of ibuprofen.

Nonsteroidal anti-inflammatory drugs with prolonged use, unfortunately, have a negative effect on the mucosa of the digestive organs, this applies to the drug Ibuprofen. Instructions for use of the tablet (400 mg) recommends taking after meals, so that the stomach does not succumb to the irritant effect of the drug.

Mechanism of action of the drug

During inflammation in the tissues are actively formed prostaglandins (physiologically active substances), an increased level of which brings the person pain. The reaction of their synthesis is accelerated by enzymes to cyclooxygenases of the 1 st and 2 nd type (COX-1 and COX-2).

Nonsteroidal anti-inflammatory drugs inhibit the formation of these catalysts, and the amount of prostaglandins rapidly decreases, since the reaction is not as intense. This mechanism of action has and Ibuprofen (400 mg). Instructions for use, the description of the drug in pharmaceutical books indicate that the product effectively removes pain, relieves inflammation and lowers the overall body temperature. The maximum concentration of the active substance is noted 1-2 hours after taking the tablet inside. The drug is excreted from the body mainly along with the urine, but in the body it accumulates in the plasma and periarticular fluid.

Advantage of tablets before other dosage forms

"Ibuprofen" is available in different doses and dosage forms. It is presented in syrups, tablets, suspensions and capsules. But if you consider "Ibuprofen" (400 mg), the instruction for its use suggests oral use, then in this dosage it is available only in tablets. This type of medicine has certain advantages:

• Convenience of reception;
• Absence of unpleasant aftertaste of the active substance due to the shell and additional components;
• Persistent effect;
• Exact dosage.

The use of tablets does not require the participation of medical personnel (as in the case of injections, for example) and compliance with sterility conditions. Tablets "Ibuprofen" of medium size, they are convenient to swallow, squeezed a small amount of water.

Indications for use

The most exhaustive document, which describes the indications for the use of the drug "Ibuprofen", is the instruction for use. Tablets (400 mg) are usually prescribed to the patient with such symptoms and illnesses:

• migraine;
• Painful menstruation;
• Inflammation and pinched nerves;
• Increased body temperature;
• toothache;
• Stiffness and unpleasant sensations in the joints with arthritis, arthrosis and non-rheumatic inflammation;
• Muscle pain;
• Inflammation of ligaments;
• Rheumatoid processes;
• Inflammation of the uterine appendages;
• Bechterew's disease;
• Manifestations of acute respiratory infections, tonsillitis, bronchitis.

The agent can be used as part of complex therapy in patients with nephrotic syndrome. It reduces the amount of protein in the urine and weakens the intensity of pain. The drug helps to reduce discomfort in the postoperative period, although it can not be the only analgesic in this case.

Ibuprofen (400 mg): instructions for use, analogues of the preparation

Tablets with this dosage are available under the following trade names:

• "MIG-400".
• Nurofen Forte.
• Faspik.
• "Brufen."
• The Buran.
• Ibuprom Max.
• Ibuprofen Nycomed.

Also there is a high-quality medicine of domestic production "Ibuprofen Hemofarm" (400 mg). Instruction for use assumes its use according to this scheme:

• With pain of moderate severity - 1 tablet 3 times a day;
• With rheumatoid inflammation of the joints - 2 tablets three times a day;
• With muscular pains and diseases of ligaments - 1,5 tablets 2-3 times a day;
• With Bekhterev's disease - 1-1.5 tablets up to 4 times a day.

These recommendations are standard for the reception of tablets with ibuprofen in a dose of 400 mg of any manufacturer. To reduce the temperature, the amount of the drug is calculated based on the patient's weight. If the mark on the thermometer reached 39.2 - you need to drink the drug from the ratio of 10 mg / kg of human weight (if the value is less, then 5 mg / kg of the patient's body weight is enough).

Contraindications

Not all people can safely use tablets "Ibuprofen" (400 mg). Instructions for the use of contraindications indicate the following:

• Ulcerative diseases of the digestive system;
• Gastritis and chronic inflammation of the intestine during periods of exacerbation;
• bronchial asthma;
• Severe violations of liver function (for example, cirrhosis or deep lesions of the blood vessels of this organ);
• Age up to 12 years;
• The last trimester of pregnancy;
• High blood pressure;
• Edema;
• Diseases of the eye nerves;
• Disorders of color perception due to ophthalmic diseases;
• Individual intolerance to the components of the drug;
• heart failure;
• Poor blood clotting.

When lactating, ibuprofen enters the breast milk, but in very low doses. To abolish the natural feeding of a newborn because of the appointment of the mother of this drug is necessary only in those cases when the woman is to have a long medication.

Than an overdose is dangerous

Before treatment, it is desirable to find out such information about the agent "Ibuprofen" (400 mg): instructions for use, form of release and contraindications. But it is important to read about safe doses of the medicine, because their excess can lead to sad consequences. Between the methods of the drug it is important to maintain a minimum interval of 6 hours, it is often not necessary to drink these tablets because of the high risk of side effects on the body. The daily dose of the drug in any case should not exceed 2.4 g.

Symptoms of taking excessive amounts of medication:

• Nausea (sometimes vomiting is possible);
• headache;
• Impaired vision;
• Lowering blood pressure;
• abdominal pain;
• dizziness;
• labored breathing;
• Blue skin.

There is no specific counteracting agent, so if you have anxious symptoms, the patient needs to rinse the stomach, ensure access to fresh air and immediately call an ambulance.

Compatibility with other drugs

Not all medicines are compatible with each other. They can enhance the side effects of each other or weaken their effectiveness. The preparation "Ibuprofen" (400 mg) is also an exception in this respect. Instruction for use warns that the medicine can not be taken with such medicines:

• Means for the treatment of hypertension (it reduces their activity and can cause an increase in blood pressure);
• Furosemide and similar diuretic drugs (ibuprofen hampers their action);
• Antitumor drugs (since ibuprofen increases their toxic effect on the body).

When treating the drug should not drink alcohol, since this combination leads to an undesirable side effect of Ibuprofen and enhances the harmful effects of alcohol.

Reviews of doctors

Doctors say that ibuprofen is one of the safest representatives of non-steroidal anti-inflammatory drugs. On its basis, a large number of medicines of the over-the-counter series are produced with high efficiency. Doctors noticed that those patients who took into account all contraindications and did not exceed the recommended dosages, from taking the medicine, only benefited.

Experts say that the drug can quickly ease the pain with neurological and orthopedic diseases. And although it does not remove the cause of their appearance, it still makes the patient's condition much easier. When the pain subsides, a person's mood rises and he calms down, and, according to doctors, the outcome of treatment depends on psychological comfort halfway.

Patient Reviews

Patients who took this drug are mostly satisfied with the speed of its action and relatively low price. Tablets well cure attacks of headache and joint pain, effectively relieve fever. Many patients with arthritis noticed that after drinking a pill in the morning, they could safely move without pain at least until lunch.

Patients with acute diseases of ENT organs (most often they were talking about angina) were satisfied with the analgesic effect of Ibuprofen. Thanks to these tablets they could swallow food and drink liquid without terrible discomfort and pain. However, to maintain a lasting effect, they had to take the drug 2-3 times a day.

The opinions of those people who are often tormented by headaches are divided. Some of them say that the medicine quickly and permanently removes the pain and for this it is enough to take 0.5-1 tablet. But patients with severe migraines who used to take prescription drugs, argue that the effect is not always as pronounced as needed.

"Ibuprofen" (400 mg): instructions for use, a description of shelf life and storage conditions

One of the advantages of tablets is a long shelf life, regardless of whether the package is opened or sealed. This is also true for the drug Ibuprofen (400 mg). Instruction for use provides a shelf life of the drug to 3 years at room temperature in a dry place. The medicine should be stored in a place protected from children, in order to avoid accidental ingestion of tablets.

Normally, ibuprofen tablets of the same shade have even edges. If any of them differ in color from the one that was originally from the opening of the package, you can not use the drug. It could become oxidized or deteriorate, so its use is unlikely to be good, but the chance of an unpleasant effect on the body is very large. The medicine is undesirable to store in the kitchen or in the bathroom (due to high humidity and temperature).

Pediatric Use

The first thing you need to pay attention to before using in childhood is the means of Ibuprofen (400 mg) - instruction for use. Dosage for a child is significantly different from that recommended for adults. Up to 12 years, the drug is not used in principle, because there are special "children's" forms of drugs with ibuprofen (candles, suspensions, syrups).

On average, a child may be recommended to take the drug 100-300 mg 3 times a day. The maximum daily allowable dose for children is 1 g. The frequency of admission should always be determined by a doctor who is aware of the diagnosis and condition of the child. For children, this drug is most often prescribed for the treatment of adolescent arthritis, rheumatism and to lower body temperature.

Is it possible to use the drug during pregnancy?

For reasons of ethics, most drugs never go through clinical trials (that is, tests in humans) during a woman's pregnancy. Therefore, data on theoretical harm or its absence are either entirely empirical or based on the results of experiments with animals. Until now, it is not known exactly how the drug such as Ibuprofen (400 mg) can affect a pregnant woman. Instructions for use indicate the data, according to which, it definitely does not need to be applied in the last 3 months of pregnancy.

But at the initial stages of bearing the fetus, the ratio of risk and benefit from the remedy should be decided by the attending physician of the woman. Given that during this period, the laying and development of all organs of the future baby takes place, it is not necessary to apply this remedy without special indications.

Additional recommendations

The drug is undesirable to take more than 4 days in a row. If symptoms increase or do not subside, you need to seek medical advice to correct the prescribed therapy. In general, the drug is well tolerated, but it is better for elderly people to start treatment with "Ibuprofen" in minimal dosages, reducing the overall duration of the course.

With pain, many people do not go to the doctor, and begin to independently seek treatment options. Now in the pharmacy quite a lot of effective drugs, which are all on hearing, among them and the drug "Ibuprofen" (400 mg). Instructions for use, reviews - this is information that you can easily find yourself or learn through your friends, but self-medication is extremely dangerous. It is much better to consult a doctor to be sure that a drug can be taken to a person, and it does not have any (sometimes not always obvious) contraindications.