Instruction "Tsetrina": indications for use, analogues. Is it possible to give "Zetrin" to children

The drug "Tsetrin" is available in suspended form in bottles of dark glass of 30 ml. In the package, a measuring cup is attached to the medicine for precise dosing. The drug is also produced in tablet form. The active substance is cetirizine.

Pharmacodynamics

The drug is a blocker of H1-histamine receptors (such information contains instructions). "Tsetrin" has an anti-allergic effect. In therapeutic doses, the medication does not pass through the BBB, and therefore has no sedative effect. The drug does not block serotonin and cholinergic receptors. The use of the drug is effective both at late and early stages of the development of an allergic disease.

Pharmacokinetics

When oral intake of a good absorption of the substance from the digestive tract. When eating food at the same time as the drug, the absorption rate does not decrease. In the blood, the maximum concentration of the drug is observed one hour after admission. The drug is actively associated with plasma proteins. Metabolism is subjected to a small amount of the dose taken. The decay process takes place in the liver cells. The withdrawal of most of the medicine is carried out unchanged in the urine.

Indications

Instruction "Tsetrin" recommends for allergic rhinitis year-round and seasonal type, hay fever (pollinosis) , angioedema. Indications for use include atopic dermatitis, urticaria (idiopathic chronic including), neurodermatitis. Assign a medicine for allergic conjunctivitis. Additionally, as part of the combined treatment, it is recommended (such information contains the instruction) "Tsetrin" in the suspended form with bronchial asthma (atopic).

Dosing regimen

The drug "Tsetrin" (pills), the use of which is allowed from the age of six, is prescribed regardless of food. It is recommended that patients with 12 years of age be prescribed 10 mg (once), from six to five milligrams twice a day. Therapeutic course - from one to four weeks. In chronic course of pathology, the duration of admission can be increased to six months. Instruction of the syrup "Tsetrin" recommends a medicine in a dose of 10 ml to patients from six years, from two years - the amount of the drug is reduced by half. In the first case, the agent is prescribed once, in the second - twice a day. If the patient has renal insufficiency, the dose should be reduced.

Contraindications to the drug "Tsetrin"

For children, the instruction establishes a restriction on age - the medication is not recommended in a suspended form until two years. To general contraindications include hypersensitivity to components. Tablets are not prescribed to patients until six years of age. Women are not recommended medication during pregnancy. In case of need to carry out therapy during the period of feeding, the doctor should warn the patient about the termination of lactation.

Information on the side effects that the instruction contains

"Cetrin" can provoke fatigue, sleep disturbance, headache, agitation. On the basis of medication, nervousness, anxiety, euphoria, dizziness, amnesia develop. Some patients experience depression, depersonalization, paralysis, thinking disorder, concentration disorder. As the instruction indicates, "Tsetrin" provokes undesirable consequences on the part of the digestive system. In particular, therapy causes dyspepsia, stomatitis, anorexia, taste perception changes. Side effects include soreness in the abdomen, gastritis, vomiting, thirst, swelling of the tongue. In some cases, the liver may be disturbed, diarrhea, flatulence, rectal bleeding, hemorrhoids. The drug negatively affects the organs of vision. At reception the conjunctivitis, a glaucoma, morbidity in opinion can develop. Rarely on the basis of the use of the medication, heart failure, hypertension, palpitations occur. In practice, cases of nasal bleeding, rhinitis, and pharyngitis have been documented. Some patients reported increased bronchial secretion. Among undesirable consequences, experts point to the possibility of developing infections in the upper respiratory tract, pneumonia, hyperventilation. Medication can cause a delay in urination, polyuria, swelling, cystitis, dysmenorrhea, vaginitis, menorrhagia, intermenstrual bleeding. In a number of cases there was a weakening of the libido when taking the remedy (this is indicated by the instruction). "Cetrin" causes pain in the back, myalgia, arthritis, muscle weakness. On the basis of therapy, bubble rashes may occur, sweating may increase. With hypersensitivity, the risk of angioedema is high. To undesirable consequences carry a seborrhea, photosensitization, an erythema, a hyperkeratosis. Among the other common side effects, there is a change (increase in weight), diabetes mellitus, fever, general malaise, "hot flashes", soreness in the mammary glands, dehydration. On the basis of treatment, there may be noise in the ears, a sense of smell, deafness, emotional lability. If there are any negative consequences when taking the medication, you should consult a doctor. Depending on the severity of the condition, you will probably need to replace the "Cetrine". An analogue of a medicine is prescribed only by a doctor. A specialist may, in particular, recommend a medication such as "Zirtek".

Overdose

If the prescribed regimen is not adhered to, drowsiness, skin rash and itching, anxiety, and delay in urinating occur. In overdose, patients also experience tremor, fatigue, tachycardia. Due to the lack of a specific antidote, the therapy is conducted in accordance with the clinical picture. To prevent poisoning, follow the recommendations that contain the instruction. "Tsetr" refers to a fairly strong means, so uncontrolled reception can lead to serious negative consequences.

Interaction with other medicines. Precautionary measures

Specialists recommend caution when taking medication together with sedatives, as well as with drugs that affect the activity of the central nervous system. The abstract does not contain information on the negative interaction of therapeutic doses with ethanol. However, experts recommend during the therapy to exclude the use of alcohol. As the instruction warns, "Cetrin" can affect the speed of psychomotor reactions. Therefore, it is not recommended to receive funds for persons whose activities are considered potentially dangerous and are associated with the management of transport or complex machinery. Treatment of children is carried out under close supervision of the pediatrician. In the absence of efficacy, the development of side effects or with the exacerbation of the symptoms of the disease should stop therapy and visit a specialist. The medicine is allowed for use within two years. Before taking the medication, you should consult a specialist and read carefully the annotation.